Signs of aseptic meningitis include: headache, fever, neck stiffness, chills, loss of appetite, and/or body aches. Aseptic meningitis is generally diagnosed when tests of a patient with signs and symptoms of meningitis do not detect bacteria. "Aseptic meningitis is a rare but serious side effect of Lamictal use," said Russell Katz, M.D., director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research. "Patients that experience symptoms should consult their health care professional immediately." Causes of aseptic meningitis include viruses and other non-bacterial infections, toxic agents, some vaccines, malignancy, and certain medications, including Lamictal. Aseptic meningitis: In 2010 the FDA issued a warning that Lamictal may cause aseptic meningitis in a subset of users. (5.7) • Medication errors involving LAMICTAL have occurred. As with other anti-epileptics, Lamictal may increase the risk of suicidal thoughts or behavior; monitor for worsening depression or mood changes. Seek medical advice with any sign of rash, fever, or swollen lymph nodes. Meningitis is a condition that causes the tissues covering your brain and spinal cord to become inflamed. What is aseptic meningitis? Aseptic meningitis Tell patients that sudden stopping of lamotrigine treatment can potentially cause uncontrolled seizures, or new or worsening mental health problems. All rights reserved. "Aseptic meningitis is a rare but serious side effect of Lamictal use," said Russell Katz, M.D., director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research. • Aseptic meningitis reported in pediatric and adult patients. Medication errors may also occur between the different formulations of LAMICTAL. The inflammation can … (3.4, 5.8, 16, 17.9) © 2021 MJH Life Sciences and Formulary Watch. Discontinuation of Lamictal should be considered if no other clear cause of meningitis is identified.” Russell Katz, director of the division of neurology products in the FDA’s Center for Drug Evaluation and Research, said that “aseptic meningitis is a rare but serious side effect of Lamictal use. Aseptic meningitis refers to inflammation of protective membranes that encapsulate the brain and spinal cord. "Aseptic meningitis is a rare but serious side effect of Lamictal use," said Russell Katz, MD, director of the Division of Neurology Products in the FDA's Center for … Methods: We performed a data mining analysis of 9 AEDs from the FDA's AERS database. "Aseptic meningitis is a rare but serious side effect of Lamictal use," said Russell Katz, M.D., director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research. In particular the names LAMICTAL or lamotrigine can be confused with names of other commonly used medications. The use of Lamictal also increases the risk of aseptic meningitis. The decision to revise the Lamictal label is based on the FDA’s identification of 40 cases of aseptic meningitis in patients taking Lamictal (from December 1994 to November 2009). Objective: The purpose of this case series is to characterize a recently identified association of the antiepileptic drug (AED) lamotrigine with aseptic meningitis based on cases reported to the Food and Drug Administration (FDA)'s Adverse Event Reporting System (AERS) database. Mood changes FDA 's AERS database adult patients meningitis do not detect bacteria 's AERS database of rash,,. The FDA 's AERS database is a condition that causes the tissues covering your and... ( 5.7 ) • Medication errors involving LAMICTAL have occurred Tell patients that experience symptoms should consult health! Their health care professional immediately. membranes that encapsulate the brain and spinal cord to inflamed... 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